Best creatine and nitric oxide bodybuilding supplement

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Why is DETONATE® considered by most as

The World's Best Pre-Workout Supplement

Dear fellow athlete,bodybuilding supplement

Like you, I fell in love with bodybuilding, and practiced this sport years (I now am 34 and have an even greater passion for it). My absolute passion for bodybuilding and sports in general have led me to compete at national and international levels, complete a national coaching certification program, and undergo University studies in the related fields of biochemistry and biomechanics.

Like you, I have invested innumerable hours at the gym, and have invested much of my earnings into my physique. My personal grocery bill has for a long time tree hundred dollars per week, without counting the thousands of dollars I have spent on nutritional and bodybuilding supplements, for most without significant or any results.bodybuilding supplement

Due to poor bodybuilding supplement cost-efficiency, I have for many years not used any nutritional supplements and attempt to achieve maximum results with only proper training and basic nutrition. This is until I met Mike Farber, a nutraceutics genie who allowed me to benefit from the first generation of REALLY effective supplements.

Let me tell you about DETONATE®, the creatine and nitric oxide booster pre-workout bodybuilding supplement which has allowed my physique to make a quantum leap and changed my work-outs for ever!creatine

Detonate Creatine and Nitric Oxide Booster bodybuilding supplement ...and immediately start enjoying these same great work-outs!

What is DETONATE®

DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement is the leading next generation muscle building supplement. Based on superior nutraceutical (combination of nutrition and pharmacology) science and premium ingredients, DETONATE® is proven to be the World's most cost-effective natural muscle building single product.

Main Benefits

DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement main benefits are:

  • Extraordinary increased muscle endurance

  • Extreme strength gains

  • Massive muscle size gains

  • Phenomenal increased recovery rate

  • Dramatic muscle pump

Other benefits include increased energy and tonus, fat loss and improved sexual health.

Detonate Creatine and Nitric Oxide Booster...And be amazed by what You Can Do!

Sport's Nutrition Science, at its Best!

DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement is the first natural health product optimized by combining individual active ingredients physiological effect with advanced delivery, pharmacokinetics and pharmacological interaction technologies.

DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement was developed by integrating 20 years of research. It was later clinically tested for efficiency in an independent laboratory under the supervision of a sports physician and is produced with absolute pharmacological rigor. As a result, the measured effects are well above any other single natural supplement!

Each ingredient in the bodybuilding supplement DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement is target delivered in a very precise dosage,  provides a specific effect by itself and synergistically acts with all all other ingredients.

The Perfect Pre-workout Bodybuilding Supplement Blend

Ready for nuclear atomic bomb type work-outs? Read this...

Other vendor's of creatine dietary supplements use creatine monohydrate, creatine citrate, creatine phosphate, tri-creatine or a blend of those types of creatine or equivalent forms of creatine. First, these forms of creatines are only partially absorbed (less than 30% absorption in most cases). Second, most (more than 60%) of the little creatine that is absorbed is degrated (cyclyzed) in creatinine, a totally ineffective and useless compound which is eliminated in the urine. As a result, not only 85% of the creatine you have paid for goes down the toilet (therefore, even if you paid your creatine supplement one quarter of the price, it is still not a good buy at all) but worst, you get very little benefit from the product. DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement uses creatine chelate, a patented form of creatine which is the only form to be totally dissolved in water and absorbed, and completely resistant to degradation. As a result, nearly 100% of the creatine you have paid for gets into your blood stream to increase your energy, muscle size, strength and endurance. The effect of the creatine chelate is also amplified by dimethylglycine (DMG), a metabolic potentiator included in DETONATE®.

Also, DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement includes L-Arginine, a compound reacting with oxygen in presence of nitric oxide synthetases to produce nitric oxide which is a potent vasodilator and increases energy. Now, L-Arginine is like the greatest 140 pounds superstar quarter back in a professional football league ; without his 350 pounds offensive lineman, he would get crushed and would never be able to score. This is why most of the L-Arginine included in the nitric oxide dietary supplements of other vendors gets broken down by the arginase enzymes and becomes useless. DETONATE® creatine and nitric oxide booster again distinguishes itself from the rest of the crowd because it includes L-Norvaline, an amino acid which acts as a competitive inhibitor, to prevents L-Arginine to be broken down by the arginase enzyme. DETONATE® creatine and nitric oxide booster also includes ginko biloba and icariin, two proven vasodilator which facilitates the transport of L-Arginine and oxygen to further increase nitric oxide production. Consequently, with DETONATE®, you'll produce more nitric oxide and have greater muscle pumps and energy than with any other dietary supplement. DETONATE® also includes niacin (or vitamin B3), another potent vasodilator when dosed in the proper amount, to increase even more the nitric oxide production. DETONATE® creatine and nitric oxide booster additionally includes synephrine, a powerfull bronchodilator, to increase the amount of oxygen available to react with L-Arginine and further increase the nitric oxide production, as well as to facilitate adenosine tri-phosphate (ATP) production and recovery between sets and after work-out.

Plus, DETONATE® includes a balanced glycerophosphate mix which multiplies by several folds the energy and already facilitated muscle pump provided by the nitric oxide production, and supported by the muscle super hydration generated by the creatine assimilation.

You may already be aware that most popular pre-workout dietary supplements provide most of their feeling of energy through massive doses of caffeine, a cheap stimulator with various adverse effects. It is important to understand that, in large dose (like used in other pre-workout creatine dietary supplements), caffeine has been proven not only to produce accomodation (this means that you need more to do the same effect - and when you stop to use it, you get a major downer and will probably gain body fat), but it has also been shown to prevent the absorption of creatine. You were impressed of the large amount of creatine in the competing pre-workout dietary supplement? Well, not only you now know that the form of creatine they use does not get absorbed well and is easily degraded, but you are now finding out that these vendors also include caffeine in doses which prevents the absorption of creatine. Bottom line, you are buying wind! You will be pleased to learn that DETONATE® has less than the equivalent in caffeine of one third of a cup of caffee, and that it provides even more powerful alertness and mind focus effects through the use of an innovative and proprietary patent pending blend consisting of target delivered cyanidins, theobromine, taurine, glucoronolactone and N-Acetyltyrosine. As a result, with DETONATE® creatine and nitric oxyde booster pre-workout dietary supplement, you will rush yourself to the gym and you will have so much energy that your soul mate will literally have to pull you away from it. Within minutes after ingesting it, you will feel energized, and that feeling will last forever, enabling you to repeatedly beat every performance record you have. In brief, your mind won't fail!

DETONATE® also provides the best mind-body connectivity by increasing nerve size and conductivity through the use of benfotiamine, and by facilitating neural function and muscle contractility through the use of Acetyl-L-carnitine (and by the way, Acetyl-L-carnitine has also been shown to increase energy production and support fat loss).  In brief, your body will follow your inexhaustible mind, all the way!

Like if all that science wasn't enough, DETONATE® additionally increases free (bioavailable) testosterone (main hormone responsible, in both men and women, for the development of skeletal muscles, and for the dominant and determined behaviors) by not only supporting its production through the supply of Zinc, Magnesiuma and Vitamin B6 (nutrients essential to the normal production of testosterone), but also by reducing the binding of tesosterone to the Sex Hormone Binding Globulin (SHBG) by the addition of 3,4-divalillyltetrahudrofuran and icariin. These effects are even amplified when DETONATE® is used in cunjunction with Testone®.

Since you know you will have tremendous workouts using DETONATE®, you will certainly be happy to find out that DETONATE® also includes specific vitamins and minerals as well as valuable active ingredients such as methyl sulfonyl methane or MSM (which protects joints and also support immune system), CoQ10 (the most powerfull superantioxidant), benfotiamines (provides a protective effect against the deleterious effects of free radicals), and rhodiola rosea (immune system booster) to facilitate recovery during an after workouts.

Now that all those wonderful ingredients are in the soup (blood stream), we must make sure that they get to where they are needed (in the muscle cells)! Unlike other vendors which limit themselves to putting the ingredients in the jar, Netrients goes all the way by ensuring that every ingredients are effectively and timely delivered where they are needed. This increases by several folds the efficiency, benefits, and value (truly!) of its products. It is presently common knowledge that insulin peaks favor the absorption of certain actives, like creatine, into cells. This is why most vendors (due to their lack of science) include large doses of dextrose, maltodextrine, and/or other sugars in their blend. Its also an inexpensive way to give taste to their product, and most importantly to increases the volume and weight of their container, which most often also increases the consumer's percieved value. So, you want to buy sugar? If such a case, I am certain that you could find a supplier willing to sell you sugar for a few dollars per ton. Let's be honnest with ourselves; who wants sugar in their training drink? No one! First, its unecessary calories, and second, sugar is absorbed much more rapidely than the other actives and generates an insulin peak way too soon. In other words, not only it gets you fat, but also it does not do the job. Simply put (let's call a horse by its name), its junk! DETONATE® contains less than one tenth of one gram (< 0.1g) of carbohydrate per serving. It is the World's first and ONLY creatine product to effectively deliver creatine without the use of carbohydrates. Its proprietary and patent protected formula includes cynaidins which boosts insulin response in normal range of glucose, so that more actives and essential elements are pushed into the muscle cells to produce their energizing and muscle building effects. It also includes fenugreek extract and chromium, which heighten and extend the insulin response to further increasing the absorption of actives and allow their later effects. DETONATE® additionally includes D-pinitol which further amplifies the insulin boost. This is why DETONATE® is the only product that not only includes everything you need to get a detonating workout, but also to ensure that all of the included ingredients reach their intended destination. I don't know about you, but I can't wait to leave this chair and try it, again!

Detonate Creatine and Nitric Oxide Booster...And RUSH to the gym!

 

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Buy Detonate Creatine and Nitric Oxide BoosterCreatine chelate, and Creatine dimalate

Creatine, also called Methyl guanidine-acetic acid, is the most popular and effective bodybuilding supplement on the market. There is one good reason why nearly all professional athletes, and three out of four of the Olympic medalists use creatine: it works, and it works well.

Detonate Creatine CycleDETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement provides creatine in the form of Albion's patented creatine malate and creatine chelate. Creatine chelate was chosen because it is better than other creatines (ex: monohydrate and phosphate) because it does not irreversibly cycle to creatinine (useless).  This process happens under normal body pH, so even if you were to take something like a buffered creatine, once it enters the blood stream it will over time disintegrate (cyclize) in skeletal muscle (8) and later be excreted by the kidneys. Unlike large molecules like tricreatine malate, creatine chelate is passively and quickly absorbed.

Creatine is a naturally occuring compound synthesized from the body stores of the amino acids glycine, L-Arginine, and methionine. The kidneys use glycine and L-Arginine to make guanidinoacetate, which the liver methylates to form creatine. It is then transported to the body's muscles through the bloodstream. While 95 – 98% of creatine is stored in muscle tissue, the amount of creatine an individual has in our body varies based on the amount of muscle mass and the level of physical activity. The average human normally has between 3.5 and 4 grams of creatine per kilogram of muscle, but muscle can store up to 5 grams of creatine per kilogram(7). On average a 160 pound person would have about 120 grams of creatine stored in their body. Increasing this amount provides numerous benefits because creatine has multiple ergogenic effects.

Creatine-PhosphocreatineIt is responsible for providing ATP to the muscle during prolonged intense efforts required in bodybuilding and other strength and power activities. ATP (adenosine tri-phosphate) is the energy substrate used by muscles to generate tension and produce work. When you are doing an intense quick burst activity - such as lifting a weight or sprinting, your muscles must contract and need a quick source of energy. This immediate energy comes from ATP. Other substrate such as carbohydrates and fat indirectly provide energy through their slow conversion into ATP.

When your muscles use ATP for energy a chemical process happens where the ATP is broken down into two simpler chemicals ADP (adenosine di-phosphate) and inorganic phosphate. This process of ATP turning into ADP releases the energy which gives your muscles the ability to contract.

Unfortunately, we do not have an endless supply of ATP. In fact, your muscles only contain enough ATP to last about 10-15 seconds at maximum exertion. In case you were wondering - no, the ADP can not be used to create more energy for your muscles. Creatine that is stored in the muscles bonds with abundant phosphorus stores in the muscles and is converted into Creatine Phosphate (CP) which reacts with the ADP in your body and turn useless ADP back into the useful energy source - ATP. More ATP in your body means more fuel for your muscles(1) via the creatine kinase system(2). Creatine's ability to enhance energy reserves in muscles comes from its muscle protein synthesizing action, while minimizing protein breakdown. More available creatine means more energy for your workouts.

Creatine has also been proven to super-hydrate muscle cells with water. Buffer Lactic Acid build-up (creatine can help buffer lactic acid that builds-up in the muscles during exercise. Lactic acid accumulation leads to that nasty burning feel you get in your muscles. Scientifically it is a complicated process - basically the creatine bonds with a Hydrogen ion and that helps delay the build up of lactic acid). Creatine additionally has recently been shown to have a direct anabolic effect (enhancing muscle Protein Synthesis).

As a result, creatine has multiple benefits for the athlete, including

  • Significantly increase lean muscle mass in just two weeks

  • Muscle volumization

  • Improve performance in high-intensity exercise and weight lifting(3-6)

  • Increase energy levels

  • Speeds up recovery rates

  • Makes muscle fibers bigger and stronger

  • Increases endurance

  • Accelerates fat loss

  • Prevent heart disease and stroke

It is interesting to note that no adverse effects have been reported in any studies. Creatine is classified as a "dietary supplement" under the 1994 Dietary Supplement Health and Education Act and is available without a prescription. Also, creatine can never be banned from any sports or international competitions (unless they ban meat, which contains creatine).

Because natural creatine production saturates below the optimal physiologic level, creatine consumption is required to increase creatine to the optimal 5g/kg of muscle mass level. While some food (especially salmon, tuna, and beef) may be able to procure about 1-2 g of creatine per day, creatine supplementation is the method of choice to obtain the desired levels. This is even more true for vegetarians who's diet might be poor in creatine and its constituent amino acids.

The best results have been noticed when creatine is combined with a high carbohydrate base, such as dextrose (glucose) and taken about one-half hour before training (on an empty stomach).

Because DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement is based on creatine chelate which does not cyclize, smaller dosage (2-3 grams per day instead of 5-15 for creatine monohydrate) are required. Also, because DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement includes other active ingredients which pushes creatine into the cells, a loading phase is not required (allowing immediate maximum results).

Detonate Creatine and Nitric Oxide Booster...And be Energized!

Nitric Oxide (N=O)

Nitric Oxide (NO), a molecule consisting of one atom of nitrogen and one atom of oxygen, is a free form gas that is produced in the body which acts as an endogenous messenger (used by the body to communicate with other cells in the body).

Nitric Oxide CycleDue to its phenomenal ergogenic effects, nitric oxide has recently capture most of the attention of the world of bodybuilding. NO has multiple positive physiologic effects including vasodilation and hemodilation. NO also increases blood flow, helping to deliver more nutrients to muscles, transmits messages between nerve cells, acts as a mediator of inflammation, is associated with the process of sensations and feeling pain, and affects the release of gonadotroptin releasing hormone, as well as the release of adrenaline from the adrenal medulla.

Some of the benefits of the above stated physiological effects are:

  • Enhances muscle hardness and vascularity

  • Provides muscle pump ("muscle swelling")

  • Harder and larger penile erections (The popular erectile dysfunction drug sildenafil citrate,Viagra, contains nitric oxide and is responsible for maintaining healthy blood flow to the penis)

  • Improved sexual sensations and performance

  • Increase in strength and endurance

  • Increase of lean muscle mass

Nitric oxide is formed in healthy vascular endothelium through. This occurs when the amino acid L-Arginine is converted into L-citruline by three isomeric forms of the Nitric Oxide Synthase (NOS) enzymes using oxygen and L-Arginine.

The bodybuilding supplement DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement formula includes targeted and precise delivery of L-Arginine, L-Norvaline and Synephrine, providing the perfect environnement (see detailed information on each of those ingredients) for optimal NO level  increases.

L-ArginineL-Arginine chelate

L-Arginine is an amino acid involved a great number of metabolic reactions and a constituent of nearly all proteins.

Most importantly for bodybuilders and athletes, it boosts the production of nitrous oxide by normalizing the L-Arginine/ADMA ratio necessary to the production of NO, promotes secretion of several hormones, including glucagon, insulin, and growth hormone and directly increases muscle protein synthesis.

L-Arginine also normalizes red blood cell density, assists in wound healing, helps remove excess ammonia from the body, stimulates immune function, increased cellular replication, regulates cholesterol levels and acts as a natural blood thinner by reducing platelet aggregation.

Some other health benefits of L-Arginine are:

  • Improves vascular function by overcoming the deleterious effects of asymmetric dimethyl L-Arginine (ADMA), a novel cardiovascular risk factor

  • Vascular function support

  • Effective in the treatment of cardiovascular dysfunction and angina(9)

  • Myocardial healing(10)

  • Congestive Heart Failure (CHF) treatment(11)

  • Hypertension treatment by reduction of systemic blood pressure(12)

  • Effectively assists in the Erectile Dysfunction (ED) treatment (13)

  • Sickle Cell Disease and Pulmonary Hypertension(14)(15)

Again, it is worthy of note that no adverse effects have been reported in any studies. L-Arginine is 100% natural and can never be banned by FDA or IOC.

L-Arginine included in the bodybuilding supplement DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement is delivered in the form of Albion patented Arginine chelate and is therefore readily absorbed.

L-Norvaline

L-NorvalineL-Norvaline is a natural amino acid present in nearly all proteins in the body.

L-Arginase major destructive (non-recycling) pathway for L-Arginine is to urea via the arginase enzyme. Interestingly, L-Norvaline it is a potent arginase inhibitor. It cuts off the destruction of L-Arginine to urea, forcing it to cycle with citrulline, making it availble for NO production(16).

Because the bodybuilding supplement DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement includes L-Norvaline, the half life of the L-Arginine included in DETONATE® as well as the one of the free L-Arginine naturally occuring in the body is extended by the protective effect of L-Norvaline against destruction of L-Arginine. As a result, their is no need for an ether functional group which decrease availability due to solubilization in fat and weight per weight concentration of L-Arginine. This makes the bodybuilding supplement DETONATE® more effective than NO boosting supplements using an ether based L-Arginine product.

Detonate Creatine and Nitric Oxide Booster...And be pumped and vascular!

Ginko Biloba

ginko-biloba-vasodilator.jpgGinko Biloba is a natural plant extract with ginkgo-flavone glycosides and terpene lactones as active ingredients.

General health support effects of Ginko Biloba include increased energy, cancer prevention, increased immunity and heart health support.

More importantly for athletes, Ginko Biloba has clinically been shown to be cause peripheral vasodilation. This allows oxygen to reach cells and react with the L-Arginine included in DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement to boost nitric oxide production, amplifying all the effects of NO described above.

Niacin

niacin-vasodilatorNiacin, also known as nicotinic acid or vitamin B3, is a water-soluble vitamin whose derivatives such as NADH, NAD, NAD+, and NADP play essential roles in energy metabolism in the living cell and DNA repair. The designation vitamin B3 also includes the corresponding amide nicotinamide, or niacinamide, whose chemical formula is C6H6N2O. Niacin has also shown to provide a strong vasodilatation effect when administered in the proper dosage.

Synephrine

SynephrineSynephrine is the main natural medicine product extract from citrus aurentium. Syneprhine is an adrenergic alkaloid similar in structure to ephedrine. Unlike ephedrine, Syneprhine delivered through Citrus Aurentium extract is perfectly legal and much safer.

Synephrine has multiple benefits to the athlete including energy production and oxygen uptake.

Citrus Aurentium has been added to the bodybuilding supplement DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement because it also:

  • Significantly increases oxygen availability for increased conversion of L-Arginine to nitric oxide

  • Dilates bronchial alveoli (Synephrine is often used Used in the treatment against allergies) to enhance oxygen uptake to react with L-Arginine boosting NO production

Other effects of synephrine include increased systolic and mean arterial blood pressure, increased cardiac index, and decreased peripheral vascular resistance.

Like many other alkaloids, synephrine interacts with the nervous system, and like ephedrine, it has a stimulation effect similar to caffeine without blocking creatine’s absorption like caffeine does (note that other manufacturers use large quantities of caffeine in their creatine formula). Unlike in formulas of other vendors, large doses of caffeine are not included in DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement for five important reasons:

  1. The dosage levels of caffeine have to be quickly increased as the subject attenuates to caffeine dose.

  2. Caffeine has been shown to inhibit the absorption of creatine.

  3. Caffeine is a vasoconstrictor which is opposite to the desired effect: vasodilatation essential to oxygen availability to L-Arginine which is responsible for NO production and pump.

  4. Caffeine increases gastric secretion which increase degradation of creatine in stomach · Increased cardiac performance

  5. Caffeine has been shown to interfere with muscle contractility

Glucoronolactone

glucuronolactone-energyGlucoronolactone is a naturally occurring chemical compound produced by the metabolism of glucose in the human liver. Glucuronolactone has been shown to improve memory retention and concentration as well as acting as an antidepressant and stimulant. It is present in some energy drinks because it fights fatigue and provide a sense of well-being.

Theobromine

theobromineTheobromine is a bitter alkaloid of the methylxanthine family, which also includes the similar compounds theophylline and caffeine. Despite its name, the compound contains no bromine. Theobromine is a stimulant frequently confused with caffeine. Theobromine has very different effects on the human body from caffeine; it is a mild, lasting stimulant with a mood improving effect, whereas caffeine has a strong, immediate effect and increases awareness. In medicine, it is used as a diuretic, vasodilator, and myocardial stimulant.

N-Acetyl tyrosine

glucuronolactone-energyTyrosine, also called L-Tyrosine, is not an essential amino acid since tyrosine can be made from the amino acid phenylalanine. Tyrosine is converted into dopamine and norepinephrine. Supplementation with both tyrosine and phenylalanine leads to alertness and arousal. Phenylalanine and tyrosine are sometimes prescribed as antidepressants, usually in combination with other nutrients and herbs that have mood elevating properties. Some doctors also recommend these amino acids for appetite control. Phenylalanine may trigger the release of an appetite-suppressing hormone in the gut called cholecystokinin. Most individuals who take either of these amino acids notice improved alertness, arousal, and mood, and slight loss in appetite.

N-Acetyl tyrosine is an acetylated derivative of the essential amino acid L-tyrosine. Acetylation enhances the stability and metabolic effect of certain amino acids. N-Acetyl Tyrosine supports brain function by improving the synthesis of the catecholamines norepinephrine and dopamine (neurotransmitters).

taurine-alertnessTaurine

Taurine or 2-aminoethanesulfonic acid is derivative of the cysteine amino acid and is abundant in the tissues of many animals (metazoa), especially sea animals. Taurine is also found in plants, fungi, and some bacterial species, but at lower levels. Taurine has been shown to increase cell insulin sensitivity and nutrients uptake into the cells.

glycerophosphateGlycerophosphate

Glycerophosphate is a naturally occuring compound which has been shown to improve cellular hydration, increase energy and facilitate a sustained muscle pump.

D-Pinitol

d-pinitol-musclePinitol is a monomethylated form of D-chiro-inositol, which is one chiral form of cyclohexitol. It is found throughout many living systems but commonly in vegtables and other plants where it thought to be involved in drought tolerance.

It is understood that in the body, pinitol is converted to D-chiro-inositol, which has roles as a secondary messenger in several metabolic processes including blood sugar control. It facilitates absorption of nutrients into cells to supports muscle growth, by increasing the insulin response.

Detonate Creatine and Nitric Oxide Booster...And just keep going until you obtain your dream body!

Ubiquinone

Ubiquinone-antioxydantUniquinone (CoQ10) is a vitamin like compound naturally produced in the human body and acting as a co-enzyme. It aids metabolic reactions, such as energy production and supports fat and carbohydrate metabolism as well as cell wall flexibility (necessary for muscle growth and injury prevention).

CoQ10 also supports general health by acting as a powerful antioxidant (prevents cancer) that protects the body from free radical damage, recycling vitamin E allowing it to remain active as an antioxidant.

As we age, our body’s production of CoQ10 declines by as much as eighty percent.

INfusamax CoQ10
included in
the bodybuilding supplement DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement allows 97% absorption of its CoQ10. CoQ10 has only a 3% absorption when directly ingested in normal pill form.

Zinc and Magnesium

Zinc (Zn) and Magnesium (Mg) are two essential minerals present in every part of the body and having a wide range of functions. These minerals have been shown to elevate blood testosterone level by as high as 30% (through stimulation of Luteinizing Hormone) when combined in the right proportions. The undisputable rôle of testosterone in most sports including bodyduilding as well as in health is the reason why the above mentionned physiological magnetizes our attention.

DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement effectively delivers both Zinc and Magnesium in the right proportions and timing, thru the use of Albion's patented chelates.

3,4-divanillyltetrahydrofuran

stinging-nettle-testosterone3,4-divanillyltetrahydrofuran is one of the active ingredients in the Urtica Laetevirens Nettle (Nettle Root) TYPE B. It has been shown to increases free testosterone by binding to SHBG (sex hormone binding globuline - protein to which androgens binds with a high affinity), provides a more anabolic environment (20,21,22, 23), as well as an hepato-protective effect (4). Prostatic cancer treatment (24). The Wikipedia (World's largest Internet dictionary) states(19): Because it contains 3,4-divanillyltetrahydrofuran, certain extracts of the nettle are used by bodybuilders in an effort to increase free testosterone by occupying sex-hormone binding globulin.

icariin-vasodilatorIcariin

Icariin is an active ingredient extracted from Horny Goat Weed (Epimedium). Epimedium is a genus of twenty-one related plant species. Animal studies have shown that epimedium may function a bit like an adaptogen (such as cordyceps, rhodiola, ashwagandha, and ginseng) by increasing levels of epinephrine, norepinephrine, serotonin, and dopamine when they are low (an energy-promoting effect), but reducing cortisol levels when they are elevated (an anti-stress effect). There is also evidence that epimedium can restore low levels of both testosterone and thyroid hormone (bringing low levels back to their normal levels) - which may account for some of the benefits of epimedium in improving libido (sex drive). Icariin has been shown to Vasodilatation, prevents HPTA depression (25,28), cortisol blocker (25), act as a testosterone mimetic (26), increases circulating testosterone (26), have an antidepressant effect (27), support erectile dysfunction (ED) treatment (28) and provide anti hepato-toxicity (29). Animal studies using epimedium have shown a reduction in bone breakdown, an increase in muscle mass, and a loss of body fat-each of which may be linked to the observed return of abnormal cortisol levels back to normal values (and rhythm). In a series of studies conducted in humans and animals by Chinese researchers, immune-system function was directly suppressed and bone loss was accelerated, by using high-dose synthetic cortisol (glucocorticoid drugs). Subsequent administration of epimedium extract reduced blood levels of cortisol and improved immune immune-system function (in the humans) and slowed bone loss and strengthened bones (in the animals).

Detonate Creatine and Nitric Oxide Booster...And dominate the weights room!

Rhodiola Rosea

rhodiola-rosea-energyExtracts of the Rhodiola Rosea root have been found to contain powerful adaptogens. Research revealed that it had a protective effect on humans against mental and physical stress.

Dimethylglycine

dimethylglycine-energyDimethylglycine (DMG) is a naturally occuring compound. It feeds glycine into various metabolic pathways and has numerous positive health aspects.

 

Cyanidins

cyanidins-energyCyanidins are natural organic compounds classified as flavonoids and anthocyanins. They are a pigment found in many redberries including but not limited to bilberry, blackberry, blueberry, cherry, cranberry, elderberry, hawthorn, loganberry, acai berry and raspberry, as well as in other fruits such as apples and plums.

Cyanidins promote an insulin response in normal glucose range. Also, like other anthocyanidins, cyanidins have antioxidant and radical-scavenging effects which, protect cells from oxidative damage.

Acetyl-L-Carnitine

Acetyl L-CarnitineAcetyl-L-Carnitine is a natural amino acid derivative. It is predominantly found in and used by cardiac and skeletal muscles. Its value to bodybuilders and other athletes comes from its many physiological effects including neural function facilitation (results in improved muscle contractility), toxic fatty acid build up prevention, and Acetyl Co-A (responsible for energy generation in the mitochondria) production.

Two of the resulting main benefits of Acetyl-L-Carnitine supplementation are increased energy and fat loss. The bodybuilding supplement DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement successfully supports the active athlete by acurately dosing and efficiently delivering Acetyl-L-Carnitine.

Benfotiamine, Vitamins B, and Vitamin C

BenfotiamineBenfotiamine a highly bioavailable form of thiamine without any toxicity. Thiamine is a B-complex vitamin.

Benfotiamine has numerous physiological effects. It acts as a potent neurotrophic agent (increases nerve growth) and improves neuron conduction velocity. Benefits are improved mind body connection, allowance for greater muscle utilization.

The production of high amounts of NO can produce some very bad side effects due to the production of peroxidation of NO. Benfotiamines have been shown to have a protective effect from the harmful side effects of overproduction of NO. Benfotiamines has been included in DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement as a safeguard so that positive effects of NO production are not outweighed by the potential for deleterious side effects both at the muscle and elsewhere. This active ingredient as well as vitamins B and C are dosed to help scavenge the free radicals that could in some instances cause cell damage (responsible for health problems and premature aging) or death. Netrients' products are designed not only for efficacy but also for the safety of those utilizing them.

Fenugreek extract

fenugreek-supplementFenugreek extract is a natural plant extract. It heighten and extends the insulin response to glucose taken during training so that more of the essential elements (including glucose and amino acids and creatine as well as most herein listed compounds included in DETONATE® creatine and nitric oxide booster) are pushed into the muscle cell and a highly anabolic state created. This results in an marked increase in strength and an increase in muscle size.

By stimulating oxygen uptake of the red blood cell by synephrine (bronchial dilator) and inhibiting the breakdown of L-Arginine DETONATE® creates an environment ripe for production of large amounts of NO over time.

 

Detonate Creatine and Nitric Oxide Booster...And immediately enjoy perfect work-out from an electrifying energy!

 

Is DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement banned from Olympics and other events

Testosterone Lean BodyDespite is proven important effect, DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement use is currently authorized by sports communities and event organisms.

Since DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement does not include any banned substances, it is impossible to mistake a DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement user from an illegal substance user.

When should I begin use DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement ?

DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement is recognized as a general health supporting natural supplement and it is generally available (you do not need a prescription to use DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement ). If you are a male and are over 18 years of age, DETONATE® creatine and nitric oxide booster  (DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement will even benefit you if you are in your seventies). It will help you remain or regain an important share of physical youth (CoQ10 and testosterone are two of the main compound controlling expression of aging). Clinical trials have demonstrated that, using the bodybuilding supplement DETONATE® creatine and nitric oxide booster, you will, in the short, medium and long term, be and feel healthier, younger and more masculine.

Detonate Creatine and Nitric Oxide Booster...And observe your growth within an hour!

How should I use DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement ?

DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement should be cycled in order to maximize effect and avoid creatine production retro-inhibition associated to long term high plasma creatine level. Follow the direction for simplicity purpose. You should not increase the intake further than the recommended dosage (guaranteed effective dosage) – increasing dosage will not improve effects.

Depending on your goals, you can stack the bodybuilding supplement DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement with other supplements to maximize results. Netrients has created various proven and cost-effective stacks to meet your specific goals.

Detonate Creatine and Nitric Oxide Booster

DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement Netrients Guarantee

As a demonstration of its commitment to excellence and of its confidence in its offer (the same is true for all Netrients products), Netrients provides every customer with a Effectiveness Guarantee. Netrients guaranties that the bodybuilding supplement DETONATE® creatine and nitric oxide booster pre-workout bodybuilding supplement will provide the above stated effects.

 

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References

  1. Murray RK and others. Harper's Biochemistry, 24th Edition. Stamford, CT: Appleton & Lange, 1996.

  2. Wallimann T, Wyss M, Brdiczka D, et al: Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem J 1992;281(pt 1):21-40

  3. Vandenberghe K, Goris M, Van Hecke P, et al: Long-term creatine intake is beneficial to muscle performance during resistance training. J Appl Physiol 1997;83(6):2055-2063

  4. Earnest CP, Snell PG, Rodriguez R, et al: The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. Acta Physiol Scand 1995;153(2):207-209

  5. Kreider RB, Ferreira M, Wilson M, et al: Effects of creatine supplementation on body composition, strength, and sprint performance. Med Sci Sports Exerc 1998;30(1):73-82

  6. Prevost MC, Nelson AG, Morris GS: Creatine supplementation enhances intermittent work performance. Res Q Exerc Sport 1997;68(3):233-240

  7. Haff GG, Potteiger JA. Creatine supplementation for the strength/power athlete. Strength and Conditioning 19(6):72-74, 1997. 

  8. Coleman E. Creatine monohydrate: a sprint performance enhancer?

  9. Walker JB: Creatine: biosynthesis, regulation, and function. Adv Enzymol Relat Areas Mol Biol 1979;50:177-242

  10. Blum A, Porat R, Rosenschein U, et al. Clinical and inflammatory effects of dietary L-L-Arginine in patients with intractable angina pectoris. Am J Cardiol 1999;83:1488-1490.

  11. Ceremuzynski L, Chamiec T, Herbaczynska-Cedro K. Effect of supplemental oral L-L-Arginine on exercise capacity in patients with stable angina pectoris. Am J Cardiol 1997;80:331-333.

  12. Watanabe G, Tomiyama H, Doba N. Effects of oral administration of L-L-Arginine on renal function in patients with heart failure. J Hypertens 2000;18:229-234.

  13. Lim DS, Mooradian SJ, Goldberg CS, et al. Effect of oral L-L-Arginine on oxidant stress, endothelial dysfunction, and systemic arterial pressure in young cardiac transplant recipients. Am J Cardiol 2004;94:828-831.

  14. Zorgniotti AW, Lizza EE Effect of large doses of the nitric oxide precursor, L-L-Arginine, on erectile dysfunction. Int J Impot Res 1994;6:33-35.

  15. Nagaya N, Uematsu M, Oya H, et al. Short-term oral administration of L-L-Arginine improves hemodynamics and exercise capacity in patients with precapillary pulmonary hypertension.

  16. Am J Respir Crit Care Med 2001;163:887-891.

  17. Mehta S, Stewart DJ, Langleben D, Levy RD. Short-term pulmonary vasodilation with L-L-Arginine in pulmonary hypertension. Circulation 1995 ;92:1539-1545.

  18. Department of Medical Physiology, Microcirculation Research Institute, Texas A&M University Health Science Center, College Station, Texas 77843-1114; and 2 Department of Chemical Engineering, University of California, Los Angeles, California 90095-1592

  19. http://en.wikipedia.org/wiki/Nettle

  20. Schottner M, Gansser D, Spiteller G. Interaction of lignans with human sex hormone binding globulin (SHBG). Z Naturforsch [C]. 1997 Nov-Dec;52(11-12):834-43. PMID: 9463941 [PubMed - indexed for MEDLINE]

  21. Schottner M, Spiteller G, Gansser D. Lignans interfering with 5 alpha-dihydrotestosterone binding to human sex hormone-binding globulin. J Nat Prod. 1998 Jan;61(1):119-21. PMID: 9461660 [PubMed - indexed for MEDLINE]

  22. Schottner M, Gansser D, Spiteller G. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Med. 1997 Dec;63(6):529-32. PMID: 9434605 [PubMed - indexed for MEDLINE]

  23. Kanter M, Coskun O, Budancamanak M. Hepatoprotective effects of Nigella sativa L and Urtica dioica L on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon tetrachloride-treated rats. World J Gastroenterol. 2005 Nov 14;11(42):6684-8. PMID: 16425366 [PubMed - indexed for MEDLINE]

  24. Krzeski T, Kazon M, Borkowski A, Witeska A, Kuczera J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther. 1993 Nov-Dec;15(6):1011-20. PMID: 7509261 [PubMed - indexed for MEDLINE]

  25. Pan Y, Zhang WY, Xia X, Kong LD. Effects of icariin on hypothalamic-pituitary-adrenal axis action and cytokine levels in stressed sprague-dawley rats. Biol Pharm Bull. 2006 Dec;29(12):2399-403. PMID: 17142971 [PubMed - in process]

  26. Pan Y, Kong L, Xia X, Zhang W, Xia Z, Jiang F. Antidepressant-like effect of icariin and its possible mechanism in mice. Pharmacol Biochem Behav. 2005 Dec;82(4):686-94. Epub 2005 Dec 27. PMID: 16380159 [PubMed - indexed for MEDLINE]

  27. Xin ZC, Kim EK, Lin CS, Liu WJ, Tian L, Yuan YM, Fu. Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities. J. Asian J Androl. 2003 Mar;5(1):15-8.

  28. Liu WJ, Xin ZC, Xin H, Yuan YM, Tian L, Guo YL. Effects of icariin on erectile function and expression of nitric oxide synthase isoforms in castrated rats. Asian J Androl. 2005 Dec;7(4):381-8. PMID: 16281085 [PubMed - indexed for MEDLINE]

  29. MI-KYEONG LEE ; YOUNG-JOO CHOI ; SANG-HYUN SUNG ; DONG-IN SHIN ; JIN-WOONG KIM ; YOUNG CHOONG KIM ; Antihepatotoxic activity of icariin, a major constitutent of Epimedium koreanum. Planta medica (Planta med.) ISSN 0032-0943. CODEN PLMEAA

DISCLAIMER: The active ingredients are naturally occurring and are found in normal food. Netrients products are fully compliance in accordance with the United States 1995 DSHEA Act regarding food supplements.

Netrients in no way advocates, supports or condones the use of any illegal substances such as anabolic steroïds. In point of fact, Netrients and its directors have dedicated themselves to developping the most advanced scientifically proven alternatives to illegal and toxic anabolic steroïds. However, the use of some of these products might cause a positive urine or blood test showing elevated testosterone levels. Athlete's and anyone else subject to performance enhancement substance testing should consult with their sanctioning organization before use.

The content of Netrients' website is provided for educational and informational purposes only and is not intended to provide medical advice. Always seek the advice of a doctor or qualified health care professional to discuss and questions or concerns you may have any medical or health-related condition. These statements have not been evaluated by the FDA. Netrients products listed here are intended solely for dietary use and are not intended to diagnose, tread, or prevent any disease.

Netrients' products names are trademark of Netrients Inc.

 

 

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